Simply put, if Money May didn't want to hurt anyone, if he were truly a pacifist, he wouldn't engage in pugilism in the first place. Neither does his claim that he cares about the well-being of his opponents.
His attacks on Bob Arum, Pacquiao's promoter, and Don King for profiting off the misery of other men don't really add anything to the conversation. Being a boxer practically guarantees that one will stand directly in harm's way, by virtue of partaking in a combat sport. This technique provides the advanced spatial and temporal resolution necessary to characterize in vivo choline levels in the striatum.įrom a translational perspective, my research is important because a better understanding of changes in neurotransmitter levels associated with aging (and the potential effects of those changes on behavior) can contribute to improved treatments for neuropathologies.If Mayweather was truly worried about his health, he would suspend his boxing career immediately, before going toe-to-toe with Junito on Saturday. I measure choline in the striatum using microelectrode array technology. My research uses behavioral tasks and neurotransmitter measurements to correlate changes in behavoir with changes in neurotransmitter levels in a model of aging. These neurons use acetylcholine to modulate dopamine as well as other neurotransmitter systems in the striatum. One of the major regulatory neurons of the striatum is the cholinergic interneuron. This area of the brain is important for motor movements as well as spatial learning and memory. The area of the brain I focus on is the striatum. It is important to understand what happens to neurotransmission during the "normal" aging process, so that we can separate out those changes from any changes associated with pathologies (e.g., Alzheimer's disease, Parkinson's disease). I am interested in aging, and specifically, changes in neurotransmitter levels associated with aging. My research focuses on neutrotransmitter signaling in the mammalian brain. 14th International Conference on In Vivo Methods. Defining glutamate transients in the awake rat: analysis of sub-second in vivo recordings. The effects of methylphenidate on glutamate signaling in the prefrontal cortex of awake freely-moving rats. 41st annual meeting – Society for Neuroscience. Diurnal recordings of second-by-second measurements of tonic and phasic glutamate release in the prefrontal cortex of awake rats using microelectrode arrays. 13th International Conference on In Vivo Methods. Regional depth analysis in rat PFC of glutamate neurotransmission in vivo: effects of anesthetics and diurnal rhythms. Vancouver, British Columbia, Canada, 2008. 12th International Conference on In Vivo Methods. Regional analysis of acetylcholine neurotransmission in rat prefrontal cortex and striatum. 37th annual meeting - Society for Neuroscience. Second-by-second microelectrode array measurements of acetylcholine release and uptake in cortex and striatum. 12th annual meeting – Institute of Biological Engineering. Second-by-second microelectrode array measurements of acetylcholine. Tonic and phasic release of glutamate and acetylcholine neurotransmission in sub-regions of the rat prefrontal cortex using enzyme-based microelectrode arrays.
Ceramic-based multisite microelectrode array for simultaneous measures of choline and acetylcholine in CNS.